The fry will be doing lots of developing in the early stages of life, so they will eat more than you think. Definately more than once a day. I would say two or three times but it depends on multiple variables. What type of food will you be feeding? My favorite is liquid fry food you buy at the pet store. Just follow the directions on the container for that. You can also just crush up some fish food so it's almost a dust in your hand. Here's a website on raising fry: http://www.guppies.com/index.php?option=com_content&task=view&id=58&Itemid=83